CJC-1295 (No DAC) (Growth Hormone Releasing Hormone Analog / Short-Acting GH Secretagogue)
Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
Molecular Weight: 3,364.70 g/mol
Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂
CAS Number: 863288-34-0
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: Store at −20°C. Protect from light and moisture.
Description
CJC-1295 (No DAC) is a synthetic analog of Growth Hormone Releasing Hormone (GHRH 1–29) designed to stimulate endogenous growth hormone (GH) release through pituitary GHRH receptor agonism.
Unlike its DAC-modified counterpart, this version lacks the Drug Affinity Complex, resulting in a shorter half-life (approximately 30 minutes) but a more physiological GH pulse pattern when administered in frequent or pulsatile intervals.
CJC-1295 (No DAC) provides a valuable research model for investigating natural GH pulsatility, pituitary sensitivity, and somatotropic rhythm modulation.
It promotes transient yet robust increases in GH secretion, supporting studies into metabolic regulation, anabolic signaling, and neuroendocrine feedback control.
This compound is frequently paired with GHRPs (e.g., Ipamorelin, GHRP-2, or GHRP-6) to examine synergistic GH pulse amplitude and frequency in controlled experimental systems.
Intended Use
This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic applications.
All handling should be performed by qualified professionals in a controlled research environment.
Key Research Applications
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Investigation of GHRH receptor activation and GH pulse physiology
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Studies on short-duration GH secretion and pituitary response cycles
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Research on metabolic regulation and IGF-1 axis activation
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Analysis of synergistic GH release with GHRP co-administration






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