Cagrilintide

Description

Cagrilintide (Amylin Receptor Agonist / Long-Acting Amylin Analog)

Molecular Formula: C₁₈₉H₂₉₁N₅₁O₅₆
Molecular Weight: 4,344.75 g/mol
Sequence: [Specify if known or leave blank for catalog entry]
CAS Number: 1893632-38-6
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: Store at −20 °C. Protect from light and moisture.

Description

Cagrilintide is a synthetic, long-acting amylin receptor agonist structurally derived from the native peptide amylin. It is used in research to investigate energy balance, appetite regulation, and metabolic signaling through amylin and calcitonin receptor pathways.

By binding to amylin and calcitonin receptors, Cagrilintide modulates gastric emptying, satiety, and nutrient intake, complementing incretin-based mechanisms. Preclinical studies suggest that combined amylin and GLP-1 receptor activation may have synergistic effects on weight regulation, insulin sensitivity, and lipid metabolism, making this compound a key tool for studying multihormonal control of metabolism.

Intended Use

This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic use.
All handling should be performed by qualified personnel in a controlled research environment.

Key Research Applications

• Investigation of amylin receptor signaling and energy balance

• Studies on appetite suppression and gastric motility

• Research on the synergistic effects of amylin and incretin pathways

• Analysis of peptide-mediated metabolic modulation