Snap-8

Description

SNAP-8 (Acetyl Octapeptide-3 / SNARE Complex Modulator)

Molecular Formula: C₄₁H₇₀N₁₆O₁₆
Molecular Weight: 888.1 g/mol
Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂
CAS Number: 868844-74-0
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: Store at −20 °C. Protect from light and moisture.

Description

SNAP-8 (Acetyl Octapeptide-3) is a synthetic peptide analog of the N-terminal domain of SNAP-25, designed to modulate SNARE complex formation involved in vesicle-to-membrane fusion. It is widely studied in cosmetic biochemistry and neurophysiology for its ability to inhibit catecholamine release and reduce neuromuscular transmission at the presynaptic level.

By competitively interfering with SNAP-25-dependent exocytosis, SNAP-8 provides a model for exploring neuropeptide-based muscle relaxation, synaptic signaling inhibition, and wrinkle attenuation mechanisms. Research demonstrates its potential synergy with other neuropeptides such as Argireline (Acetyl Hexapeptide-8), making it valuable for studying neurotransmitter modulation and dermal physiology.

Intended Use

This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic applications.
All handling should be performed by qualified professionals in a controlled research environment.

Key Research Applications

• Studies on SNARE complex modulation and synaptic vesicle fusion

• Research on neuropeptide mechanisms of muscle relaxation

• Investigation of peptide synergy in cosmetic and neuromodulatory models

• Analysis of neurotransmitter release inhibition pathways