Testagen

Description

Testagen (Pituitary–Thyroid Bioregulatory Tetrapeptide / Endocrine Signaling Modulator)

Molecular Formula: C₁₇H₂₉N₅O₉
Molecular Weight: 447.4 g/mol
Sequence: Lys-Glu-Asp-Gly (KEDG)
CAS Number: 77614-16-5 (reported)
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: Store at −20 °C. Protect from light and moisture.

Description

Testagen is a short synthetic bioregulatory peptide consisting of the amino acid sequence Lys-Glu-Asp-Gly (KEDG).
It has been developed for research into pituitary and thyroid axis regulation, with focus on how short peptides influence endocrine feedback loops, hormonal secretion, and gene expression.

Through interaction with nuclear DNA and histone proteins, Testagen is believed to modulate transcriptional activity associated with thyroid-stimulating hormone (TSH) production and overall pituitary function.
Experimental data from peptide bioregulation studies suggest its role in maintaining hormonal homeostasis, metabolic regulation, and reproductive axis stability during stress or age-related decline.

As part of the broader class of cytomedin peptides, Testagen serves as a model for exploring epigenetic regulation, peptide–nucleus signaling, and endocrine rejuvenation mechanisms.

Intended Use

This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic applications.
All handling should be performed by qualified professionals in a controlled research environment.

Key Research Applications

• Investigation of pituitary–thyroid feedback regulation and TSH signaling

• Studies on endocrine peptide modulation and hypothalamic–pituitary–gonadal (HPG) axis effects

• Research on short peptide gene regulation and histone/DNA binding mechanisms

• Analysis of age-related hormonal decline, immune signaling, and cellular regeneration