HGH Frag 176-191

Description

HGH Frag 176–191 (Human Growth Hormone Fragment / Lipolytic Peptide Analog)

Molecular Formula: C₃₉H₆₀N₁₀O₁₃
Molecular Weight: 1,817.12 g/mol
Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Gly-Ser-Cys-Gly-Phe
CAS Number: 221231-10-3
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: Store at −20 °C. Protect from light and moisture.

Description

HGH Frag 176–191 is a synthetic peptide fragment representing amino acids 176–191 of the human growth hormone (HGH) sequence.
This truncated analog retains the lipolytic (fat-burning) domain of HGH but lacks the growth-promoting and diabetogenic activities associated with the full hormone.

Research indicates that HGH Frag 176–191 acts by stimulating lipolysis and inhibiting lipogenesis, particularly in adipose tissue.
It is believed to work through β-adrenergic-independent mechanisms, modulating the activity of adenylyl cyclase and cAMP-dependent signaling pathways, resulting in enhanced fat metabolism and energy mobilization.

Because it mimics HGH’s metabolic benefits without significant IGF-1 elevation or mitogenic activity, HGH Frag 176–191 is an important model for studying targeted fat metabolism, peptide-based hormone selectivity, and metabolic regulation.

Intended Use

This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic applications.
All handling should be performed by qualified professionals in a controlled research environment.

Key Research Applications

• Investigation of selective HGH fragment bioactivity and receptor interactions

• Studies on lipolysis, adipocyte metabolism, and fat oxidation

• Research on peptide-based modulation of metabolic signaling pathways

• Analysis of cAMP-mediated energy regulation and lipid turnover