AICAR Tablets

Description

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AICAR (5-Aminoimidazole-4-carboxamide Ribonucleotide / AMPK Pathway Activator)

Form: Tablet
Concentration: 10 mg per tablet
Quantity per Bottle: 30 tablets

Molecular Formula: C₉H₁₅N₄O₈P
Molecular Weight: 338.21 g/mol
CAS Number: 2627-69-2
Purity: ≥98% (HPLC)
Storage: Store in a cool, dry place away from light and moisture.

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Description

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is an AMP-activated protein kinase (AMPK) activator used in research exploring energy metabolism, mitochondrial biogenesis, and cellular stress response.
Once inside cells, AICAR is phosphorylated to ZMP (AICAR monophosphate), an AMP analog that directly activates AMPK, mimicking the effects of cellular energy depletion or exercise.

Activation of AMPK by AICAR has been shown to enhance glucose uptake, increase fatty acid oxidation, and improve mitochondrial efficiency.
These properties make it a valuable model compound for studying metabolic diseases, endurance physiology, insulin sensitivity, and mitochondrial adaptation.

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Intended Use

This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic applications.
All handling should be performed by qualified professionals in a controlled research environment.

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Key Research Applications

• Investigation of AMPK activation and downstream metabolic signaling

• Studies on mitochondrial biogenesis, energy expenditure, and oxidative metabolism

• Research on glucose regulation, insulin sensitivity, and endurance adaptation

• Analysis of exercise-mimetic compounds and metabolic stress pathways