KPV Tablets

Description

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KPV (α-MSH Fragment Peptide / Anti-Inflammatory & Immunomodulatory Tripeptide)

Form: Tablet
Concentration: 500 mcg per tablet
Quantity per Bottle: 30 tablets

Molecular Formula: C₁₈H₂₇N₅O₄
Molecular Weight: 377.44 g/mol
Sequence: Lys-Pro-Val
CAS Number: 80498-15-3
Purity: ≥98% (HPLC)
Storage: Store in a cool, dry place away from light and moisture.

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Description

KPV is a bioactive tripeptide fragment derived from alpha-melanocyte-stimulating hormone (α-MSH), consisting of Lysine–Proline–Valine.
It is a potent anti-inflammatory and immunomodulatory compound that operates through melanocortin receptor signaling, primarily the MC1R receptor subtype.

In preclinical studies, KPV has shown the ability to suppress pro-inflammatory cytokine production (TNF-α, IL-1β, IL-6), reduce NF-κB activation, and enhance epithelial barrier integrity.
Its small molecular size and oral stability make it a model peptide for research into gut inflammation, autoimmune modulation, and epithelial repair mechanisms.

When administered orally, KPV demonstrates notable resistance to enzymatic degradation, allowing it to be used in research exploring localized and systemic anti-inflammatory signaling in intestinal and dermal tissues.

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Intended Use

This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic applications.
All handling should be performed by qualified professionals in a controlled research environment.

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Key Research Applications

• Investigation of melanocortin receptor (MC1R) activation and signaling pathways

• Studies on inflammation suppression and cytokine modulation

• Research on epithelial barrier repair and wound healing mechanisms

• Analysis of oral peptide stability and systemic anti-inflammatory potential