5-Amino-1MQ Tablets

Description

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5-Amino-1MQ (Nicotinamide N-Methyltransferase Inhibitor / Metabolic Modulator)

Form: Tablet
Concentration: 50 mg per tablet
Quantity per Bottle: 25 tablets

Molecular Formula: C₇H₁₀N₂O
Molecular Weight: 138.17 g/mol
CAS Number: 252331-84-7
Purity: ≥98% (HPLC)
Storage: Store in a cool, dry place away from light and moisture.

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Description

5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in methylation metabolism and cellular NAD⁺ regulation.
By inhibiting NNMT, 5-Amino-1MQ reduces the methylation of nicotinamide, conserving NAD⁺ availability and enhancing cellular energy efficiency and lipid metabolism.

Preclinical research indicates that 5-Amino-1MQ increases lipolysis, decreases adipocyte size, and improves metabolic rate and insulin sensitivity.
It has also been explored for its potential role in modulating sirtuin activity, methyl donor utilization, and obesity-related metabolic signaling pathways.

As an orally bioavailable metabolic regulator, it serves as a model compound for studying cellular methylation balance, energy expenditure, and NAD⁺-linked enzymatic systems.

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Intended Use

This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic applications.
All handling should be performed by qualified professionals in a controlled research environment.

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Key Research Applications

• Investigation of NNMT inhibition and methylation pathway regulation

• Studies on NAD⁺ metabolism, mitochondrial efficiency, and energy balance

• Research on lipid oxidation, adipocyte function, and obesity mechanisms

• Analysis of sirtuin activation and metabolic health biomarkers