DSIP

Description

DSIP (Delta Sleep-Inducing Peptide / Neuroendocrine Modulator)

Molecular Formula: C₃₅H₄₈N₁₀O₈
Molecular Weight: 848.83 g/mol
Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
CAS Number: 62568-57-4
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: Store at −20 °C. Protect from light and moisture.

Description

Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring nonapeptide discovered in the hypothalamus and studied for its role in sleep regulation, neuroprotection, and endocrine balance.
It influences GABAergic and serotonergic signaling pathways and is thought to normalize sleep–wake cycles, reduce stress-induced cortisol secretion, and modulate pituitary hormone release (notably GH and LH).

Preclinical data show that DSIP can enhance slow-wave (delta) sleep, improve recovery and adaptation to stress, and provide cytoprotective effects on neural tissue through antioxidant and mitochondrial-supportive mechanisms.
It is also of interest in studies examining hypothalamic-pituitary axis regulation, circadian rhythm synchronization, and fatigue resistance.

Intended Use

This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic applications.
All handling should be performed by qualified professionals in a controlled research environment.

Key Research Applications

• Investigation of neuropeptide control over sleep architecture and circadian rhythm

• Studies on stress adaptation, cortisol modulation, and pituitary signaling

• Research on neuroprotection, mitochondrial stability, and antioxidant pathways

• Analysis of peptide-mediated endocrine and neurological interactions