GHRP-2

Description

GHRP-2 (Growth Hormone Releasing Peptide-2 / Ghrelin Receptor Agonist)

Molecular Formula: C₄₅H₅₅N₉O₆
Molecular Weight: 818.0 g/mol
Sequence: D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂
CAS Number: 158861-67-7
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: Store at −20°C. Protect from light and moisture.

Description

GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide and a potent ghrelin receptor (GHSR-1a) agonist known for its ability to stimulate pulsatile growth hormone (GH) release from the anterior pituitary.

It acts independently of GHRH by binding to the GH secretagogue receptor, enhancing endogenous GH secretion through calcium and phospholipase C signaling pathways.
GHRP-2 has been widely studied for its effects on muscle growth, lipid metabolism, immune regulation, and recovery processes.

Compared to GHRP-6, GHRP-2 produces a stronger GH release with reduced stimulation of appetite, prolactin, and cortisol, making it a preferred model for studying GH axis modulation without confounding endocrine effects.

In research settings, it’s frequently paired with CJC-1295 or Ipamorelin to explore synergistic effects on GH/IGF-1 secretion and tissue anabolism.

Intended Use

This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic applications.
All handling should be performed by qualified professionals in a controlled research environment.

Key Research Applications

• Investigation of GH secretagogue receptor activation and pituitary signaling

• Studies on GH pulsatility and IGF-1 pathway modulation

• Research on muscle recovery, lipid metabolism, and anabolic physiology

• Analysis of ghrelin analogs and hypothalamic-pituitary axis control