GLP-2

Description

Tirzepatide (GLP-1/GIP Receptor Dual-Agonist)

Molecular Formula: C₂₂₅H₃₄₈N₄₈O₆₈
Molecular Weight: 4,814.73 g/mol
Sequence: [Specify if known or leave blank for catalog entry]
CAS Number: 2023788-19-2
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: Store at −20 °C. Protect from light and moisture.

Description

Tirzepatide is a synthetic dual-agonist peptide that activates both GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. Its dual-incretin mechanism provides a unique tool for exploring how combined receptor signaling influences glucose homeostasis, lipid metabolism, and energy balance.

Through concurrent GLP-1 and GIP receptor engagement, Tirzepatide demonstrates synergistic effects on insulin secretion, appetite regulation, and adipose tissue metabolism in preclinical models. This dual activation allows researchers to investigate enhanced metabolic signaling cascades and their downstream effects on nutrient utilization, β-cell responsiveness, and body-weight modulation.

Intended Use

This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic use.
All handling should be performed by qualified personnel in a controlled research environment.

Key Research Applications

• Investigation of incretin signaling and metabolic regulation

• Studies on glucose homeostasis and insulin sensitivity

• Research on energy expenditure and appetite control

• Evaluation of peptide receptor co-activation mechanisms