Mazdutide (GLP-1 / Glucagon Receptor Dual-Agonist)
Molecular Formula: C₂₁₀H₃₂₂N₄₆O₆₇ (approximate) Wikipedia+1
Molecular Weight: ~ 4,800 g/mol (approximate)
Sequence: [Specify if known or leave blank for catalog entry]
CAS Number: 2259884-03-0 Wikipedia+1
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: Store at −20 °C. Protect from light and moisture.
Description
Mazdutide is a synthetic long-acting dual agonist targeting both the GLP-1 (glucagon-like peptide-1) receptor and the glucagon receptor (GCGR). Drugs.com+2sciencedirect.com+2
As an analogue of mammalian oxyntomodulin, Mazdutide’s mechanism is designed to harness incretin-effects (via GLP-1R activation) for enhancing insulin secretion and reducing appetite, while concurrently engaging GCGR to increase energy expenditure and improve hepatic fat metabolism. PR Newswire+1
In clinical studies it has shown promising metabolic benefits including weight reduction, improved glycemic control (HbA₁c reductions), lowered liver fat, lowered waist circumference and improvements in cardiometabolic markers. PR Newswire
Intended Use
This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic purposes.
All handling should be performed by qualified professionals in a controlled research environment.
Key Research Applications
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Investigation of dual-agonist peptide receptor activation (GLP-1 + glucagon) in metabolic regulation
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Studies on weight regulation, adiposity, hepatic fat content and energy expenditure
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Research on glucose homeostasis, insulin sensitivity, and hepatometabolic function
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Evaluation of cardio-metabolic biomarkers under peptide-based interventions






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