Description
Tamoxifen (Selective Estrogen Receptor Modulator / Estrogen Antagonist-Agonist)
Form: Tablet
Concentration: 20 mg per tablet
Quantity per Bottle: 30 tablets
Molecular Formula: C₂₆H₂₉NO
Molecular Weight: 371.51 g/mol
CAS Number: 10540-29-1
Purity: ≥98% (HPLC)
Storage: Store in a cool, dry place away from light and moisture.
Description
Tamoxifen is a selective estrogen receptor modulator (SERM) that binds to estrogen receptors (ERα and ERβ), exhibiting both antagonistic and agonistic activity depending on the target tissue.
It is primarily used in research examining estrogen signaling, endocrine feedback, and receptor-mediated transcriptional regulation.
In endocrine and androgen research models, Tamoxifen is known to block estrogenic feedback at the hypothalamus and pituitary, leading to increased LH and FSH secretion and subsequently stimulated endogenous testosterone production.
It is also widely used as a post-androgen recovery model compound and to study estrogen receptor dynamics, coactivator recruitment, and ER-modulated gene expression in various tissues.
Intended Use
This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic applications.
All handling should be performed by qualified professionals in a controlled research environment.
Key Research Applications
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Investigation of estrogen receptor (ERα/ERβ) modulation and gene transcription regulation
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Studies on hypothalamic-pituitary-gonadal (HPG) axis recovery and hormonal feedback
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Research on SERM pharmacodynamics and selective tissue agonism/antagonism
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Analysis of estrogen-sensitive pathways in metabolic and reproductive models
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