Description
Tesofensine (Triple Monoamine Reuptake Inhibitor / Appetite and Energy Modulation Compound)
Form: Tablet
Concentration: 500 mcg per tablet
Quantity per Bottle: 60 tablets
Molecular Formula: C₁₇H₂₃NO₄
Molecular Weight: 305.37 g/mol
CAS Number: 402856-42-2
Purity: ≥98% (HPLC)
Storage: Store in a cool, dry place away from light and moisture.
Description
Tesofensine is a synthetic piperidine derivative that functions as a triple monoamine reuptake inhibitor (SNDRI) — blocking the presynaptic reuptake of serotonin, norepinephrine, and dopamine.
Originally developed as a Parkinson’s and Alzheimer’s candidate, it has become a research compound of interest in energy metabolism and appetite regulation studies.
Through combined monoaminergic stimulation, Tesofensine enhances sympathetic tone, reduces food intake, and increases energy expenditure by modulating hypothalamic signaling involved in satiety and metabolic rate.
In preclinical research, it has demonstrated significant body weight reduction, lipid metabolism improvement, and positive effects on insulin sensitivity.
Intended Use
This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic applications.
All handling should be performed by qualified professionals in a controlled research environment.
Key Research Applications
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Investigation of monoamine transporter inhibition (serotonin, dopamine, norepinephrine)
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Studies on central appetite regulation and metabolic rate modulation
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Research on energy balance, weight reduction, and neurochemical control of feeding behavior
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Analysis of neurostimulant effects on sympathetic activity and thermogenesis
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