VIP

Description

VIP (Vasoactive Intestinal Peptide / Neuropeptide Receptor Agonist)

Molecular Formula: C₁₄₇H₂₃₉N₄₃O₄₂S
Molecular Weight: 3,326.8 g/mol
Sequence: HSDAVFTDNYTRLRKQMAVKKYLNSILN
CAS Number: 33515-09-2
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: Store at −20 °C. Protect from light and moisture.

Description

Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide belonging to the secretin/glucagon peptide family.
It acts as a potent agonist of VPAC1 and VPAC2 receptors, influencing smooth muscle relaxation, vasodilation, immune modulation, and circadian rhythm regulation.

In research settings, VIP is used to study neuroimmune communication, bronchodilation, gastrointestinal motility, and anti-inflammatory signaling.
Its activity through cAMP-mediated pathways provides a key model for investigating neuropeptide receptor pharmacology, G-protein signaling, and peptide-mediated tissue protection.

Due to its diverse physiological roles, VIP is of particular interest in studies on neurodegenerative conditions, inflammatory diseases, and pulmonary function.

Intended Use

This product is intended for laboratory research use only.
It is not for human consumption, diagnostic, or therapeutic use.
All handling should be performed by qualified professionals in a controlled research environment.

Key Research Applications

• Investigation of VPAC1/VPAC2 receptor activation and signaling pathways

• Studies on vasodilation, smooth muscle relaxation, and bronchodilation

• Research on neuroimmune modulation and cytokine suppression

• Analysis of peptide effects in circadian, pulmonary, and gastrointestinal systems